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  Previous issue (2019. Vol. 11, no. 2)

Psychological-Educational Studies

Former Title: Psychological Science and Education psyedu.ru

Publisher: Moscow State University of Psychology and Education

ISSN (online): 2587-6139

DOI: http://dx.doi.org/10.17759/psyedu

License: CC BY-NC 4.0

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Genetic Mechanisms of Mental Disturbances: Chromosomal and Genomic Disorders 1043

Yurov I.Yu., professor , RANH, Moscow, Russia
Vorsanova S.G., professor, head, laboratory at the Institute of pediatrics and pediatric surgery, Rosmedtehnologii. Leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents” at the Moscow State University of Psychology and Education, Moscow, Russia
Yurov Yu.B., professor, head of laboratory at the Research center of mental health. Leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents” at the Moscow State University of Psychology and Education., Moscow, Russia
Abstract
Currently, it is well known that genetic anomalies significantly contribute to pathogenesis of different mental disturbances, including such diseases as mental retardation, autism, schizophrenia and Alzheimer’s disease. More precisely, up to 50% of cases of these diseases can be associated with gene, chromosomal and genomic mutations. In this context, providing for medical and psychological help at modern level for individuals affected by these diseases would be incomplete without application of newly introduced methods for genome analysis to diagnose and to identify mechanisms of neuropsychiatric disorders. Here, a brief overview of current advances in analyses of genetic mechanisms of mental disturbances and developments in diagnosis of chromosomal and genomic disorders are given.

Keywords: autism, Alzheimer’s disease, genome, DNA, mental retardation, chromosomal abnormalities, schizophrenia.

Column: Clinical Psychology

For Reference

References
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