Magnetoencephalography (MEG) in focal cortical dysplasia (FCD) *750
Paetau R., Ph.D., Department of Gynaecology and Paediatrics, Epilepsy Unit and Department of Clinical Neurophysiology, Финляндия, email@example.com Wilenius J., Department of Clinical Neurophysiology, Jorvi Hospital, Hospital District of Helsinki and Uusimaa, Espoo, Finland, Финляндия, firstname.lastname@example.org
* This study was supported by Helsinki and Uusimaa Hospital District funding for product development (Project MLE82TK005) and by the SalWe ResearchProgram for Mind and Body (Tekes - the Finnish Funding Agency for Technology and Innovation grant 1104/10).
Ссылка для цитирования
Magnetoencephalography (MEG) and EEG reflect postsynaptic currents in
pyramidal cells. MEG is selectively sensitive to tangential currents, typically
produced by fissure walls. Because the bottom of sulci are predilection sites
for FCD lesions, we investigated whether MEG results could predict clinical
outcome in epilepsy surgery patients with FCD. We specially focused on patients
with no visible lesions on magnetic resonance imaging (MRI).
Engel JJ. (1993) Outcome with respect to
epileptic seizures. In Engel JJ (Ed) Surgical treatment of the epilepsies.
Raven Press, New York, pp.609-621
Frater JL, Prayson RA, Morris III HH, Bingaman
WE. (2000) Surgical pathologic findings of extratemporal-based intractable
epilepsy: A study of 133 consecutive resections. Archives of Pathology &
Laboratory Medicine 124:545-549.
Krsek P, Maton B, Jayakar P, Dean P, Korman B, Rey
G, Dunoyer C, Pacheco-Jacome E, Morrison G, Ragheb J, Vinters HV, Resnick T,
Duchowny M. (2009) Incomplete resection of focal cortical dysplasia is the
main predictor of poor postsurgical outcome. Neurology 72:217-223.
Palmini A, Najm I, Avanzini G, Babb T, Guerrini R,
Foldvary-Schaefer N, Jackson G, Luders HO, Prayson R, Spreafico R, Vinters
HV. (2004) Terminology and classification of the cortical dysplasias.
Sisodiya SM. (2004) Surgery for focal
cortical dysplasia. Brain; a journal of neurology 127:2383-2384.
Widjaja E, Otsubo H, Raybaud C, Ochi A, Chan D,
Rutka JT, Snead OC,3rd, Halliday W, Sakuta R, Galicia E, Shelef I, Chuang
SH. (2008) Characteristics of MEG and MRI between taylor's focal cortical
dysplasia (type II) and other cortical dysplasia: Surgical outcome after
complete resection of MEG spike source and MR lesion in pediatric cortical
dysplasia. Epilepsy research 82:147-155.