Factors Influencing the Success Of Autism Spectrum Disorders Overcoming 1816
Doctor of Biology, Professor, Head of Research Laboratory, Federal Resource Center for Organization of Comprehensive Support to Children with ASD, Moscow State University of Psychology and Education, Moscow, Russia
PhD in Psychology, Senior Researcher, Federal Resource Center for Organization of Comprehensive Support to Children with Autism Spectrum Disorders, Moscow State University of Psychology and Education, Moscow, Russia
PhD in Medicine, Leading Researcher, Research Clinical Institute of Pediatrics Named After Academi¬cian Yuri Veltishchev, Health and Social Welfare Ministry, Moscow, Russia
PhD in Biology, Leading Researcher, Federal Resource Center for Organization of Comprehensive Support for Children with ASD, Moscow State University of Psychology and Education, Moscow, Russia
Senior Lecturer, Department of Neuro- and Patho-Psychology, Faculty of Clinical and Special Psychology, Moscow State University of Psychology and Education, Research Fellow, Department of Medical Psychology, Research Center of Mental Health, RAMS, Moscow, Russia
junior researcher, R&EC «Neurobiological Diagnostics of Hereditary Mental Disor¬ders of Children and Adolescents», MSUPE, Moscow, Russia
e-mail: : email@example.com
PhD in Psychology, Senior Researcher, Federal Resource Center for Organization of Comprehensive Support to Children with ASD, Moscow State University of Psychology & Education, Moscow, Russia
PhD in Psychology, Senior Researcher, Mental Health Research Center, Moscow, Russia
Junior Researcher, FRC MSUPE, Moscow, Russia
Junior Researcher,, R&EC «Neurobiological Diagnostics of Hereditary Mental Disor¬ders of Children and Adolescents», MSUPE, Moscow, Russia
professor , RANH, Moscow, Russia
professor, head, laboratory at the Institute of pediatrics and pediatric surgery, Rosmedtehnologii. Leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents” at the Moscow State University of Psychology and Education, Moscow, Russia
professor, head of laboratory at the Research center of mental health. Leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents” at the Moscow State University of Psychology and Education., Moscow, Russia
No more than 10—20% of children with autism, as becoming adults can adapt to a relatively independent life. Despite many publications dedicated to autism, relatively little work has examined the output characteristics and pathomorphosis of psychic and cognitive disorders in people with autism spectrum disorders (ASD). Only few longitudinal studies allow us to represent what happens in later life with people who have ASD. For conducting effective correctional interventions overcomingwith children with ASD there is need to identify predictors of successful overcome of disorders. The basis for the study, conducted by a team of psychologists and neuroscientists, was the assumption that the information about the features of violations of basic neurobiological mechanisms in people with autism spectrum disorders should determine the tactics of assistance. Genetic, neurophysiological and psychological factors, causing more successful overcoming of these disorders in children are revealed.
Vorsanova S.G., Iourov I.Y., Demidova I.A., Kurinnaya
O.S., Voinova V.Y., Kravets V.S., Beresheva A.K., Kolotii A.D., Saprina E.A.,
Solov’ev I.V., Yurov Y.B. Autisticheskie rasstroistva i khromosomnye
variatsii v sem’yakh detei s autizmom [Autism spectrum disorders and copy
number variations in families with autistic children]. Psikhiatriya
[Psychiatry], 2010. no. 3. (In Russ.)
Luriya A.R. Lektsii po obshchei psikhologii
[Lectures on general psychology]. Saint-Petersburg: Publ. Piter, 2007. 320
Iourov I.Y., Vorsanova S.G., Yurov Y.B.
Geneticheskie mekhanizmy narusheniya psikhiki: khromosomnye i genomnye bolezni
[Genetic mechanisms of mental disorders: chromosomal and genomic diseases].
Elektronnyi zhurnal «Psikhologicheskaya nauka i obrazovanie»
[E-journal “Psychological Science and Education psyedu.ru”], 2010, no.
5. URL: http://psyedu.ru/journal/2010/5/Yurov_Vorsanova_Yurov.phtm. (Accessed
Iourov I.Y., Vorsanova S.G., Kurinnaya O.S.,
Sil’vanovich A.P., Yurov Yu.B. Geneticheskie aspekty psikhologicheskikh i
povedencheskikh narushenii u detei s autisticheskimi rasstroistvami i
trudnostyami v obuchenii: diagnostika genomnykh i khromosomnykh narushenii s
ispol’zovaniem DNK-mikrochipov [Genetic aspects of psychological and behavioral
disfunctions in children with autism spectrum disorders and learning
disability: diagnosis of chromosomal and genomic abnormalities using DNA
microarrays]. Sovremennye problemy nauki i obrazovaniya [Modern
problems of science and education], 2012. no. 3. URL:
http://www.science-education.ru/ ru/article/view?id=6449. (Accessed
Benvenuto A., Moavero R., Alessandrelli R., Manzi B.,
Curatolo P. Syndromic autism: causes and pathogenetic pathways // World J
Pediatr. 2009. V. 5. № 3.
Budimirovic D.B., Kaufmann W.E. What can we learn
about autism from studying Fragile X Syndrome? // Dev Neurosci. 2011. №
Levy S.E., Mandell D.S., Schultz R.T. Autism //
Lancet. 2009. V. 374. № 9701.
Howlin P., Magiati I., Charman T. Systematic review
of early intensive behavioral interventions for children with autism // Am J
Intellect Dev Disabil. 2009. V. 114. № 1.
Iourov I.Y., Vorsanova S.G., Yurov Y.B. Chromosomal
mosaicism goes global // Molecular Cytogenetics. 2008. V. 1.
Iourov I.Y., Vorsanova S.G., Yurov Y.B. Molecular
cytogenetics and cytogenomics of brain diseases // Current Genomics. 2008. V.
9. № 7.
Iourov I.Y., Vorsanova S.G., Liehr T. et al.
Increased chromosome instability dramatically disrupts neural genome integrity
and mediates cerebellar degeneration in the ataxia-telangiectasia brain //
Human Molecular Genetics. 2009. V. 18. № 14.
Raine A. The SPQ: a scale for the assessment of
schizotypal personality based on DSM-III-R criteria // Schizophr Bull. 1991.
V.17. № 4.
Schopler E., Reichler R.J., Bashford A., Lansing M.D.,
Marcus L.M. Psychoeducational Profile-Revised (PEP-R): V. I. Baltimore,
Schopler E., Reichler R.J., Renner B.R. The
childhood autism rating scale (CARS) for diagnostic screening and
classification of autism. N.Y., 1986.
Vorsanova S.G., Kolotii A.D., Sharonin V.O., Soloviev
I.V., Yurov Y.B. FISH analysis of microaberrations at telomeric and
subtelomeric regions in chromosomes of children with mental retardation // Am J
Hum Genet. 1998. V. 63. № suppl 4.
Vorsanova S.G., Iourov I.Y., Demidova I.A. et al.
Variability in the heterochromatin regions of the chromosomes and chromosomal
anomalies in children with autism: identification of genetic markers of
autistic spectrum disorders // Neurosci Behav Physiol. 2007. V. 37. № 6.
Vorsanova S.G., Voinova V.Yu., Yurov I.Yu., Kurinnaya
O.S., Demidova I.A., Yurov Y.B. Cytogenetic, molecular-cytogenetic, and
clinical-genealogical studies of mothers of children with autism: a search of
familial genetic markers of autistic disorders // Neuroscience and Behavioural
Physiology. 2010. V. 40. № 7.
Wing L. Autistic Disorder Interview. L.,
Yurov Y.B., Vorsanova S.G., Iourov I.Y. et al.
Unexplained autism is frequently associated with low-level mosaic aneuploidy //
J Med Genet. 2007. V. 44. № 8.