Irina Sergeevna Balan

Member of editorial council, member of editorial board of “Extreme Psychology and Personal Safety” journal

Country USA
Academic degrees and titles Ph.D. in Neuroscience
Occupation and current place of work Research Associate, Department of Psychiatry, Bowles Center for Alcohol Studies, University of North Carolina
E-mail address balanirina2013@gmail.com
Scopus ID 56501777100
Main scientific publications
  1. Balan I, Patterson R, Boero G, Krohn H, O'Buckley TK, Meltzer-Brody S, Morrow AL. Brexanolone therapeutics in post-partum depression involves inhibition of systemic inflammatory pathways. EBioMedicine. 2023 Mar;89:104473. doi: 10.1016/j.ebiom.2023.104473. Epub 2023 Feb 16. PMID: 36801618; PMCID: PMC9984433.
  2. Balan I, Aurelian L, Williams KS, Campbell B, Meeker RB, Morrow AL. Inhibition of human macrophage activation via pregnane neurosteroid interactions with toll-like receptors: Sex differences and structural requirements. Front Immunol. 2022 Jul 29;13:940095. doi: 10.3389/fimmu.2022.940095. PMID: 35967446; PMCID: PMC9373802.
  3. Balan I, Aurelian L, Schleicher R, Boero G, O'Buckley T, Morrow AL. Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-dependent toll-like receptors. Transl Psychiatry. 2021 Feb 26;11(1):145. doi: 10.1038/s41398-021-01266-1. PMID: 33637705; PMCID: PMC7909379.
  4. Balan I, Beattie MC, O'Buckley TK, Aurelian L, Morrow AL. Endogenous Neurosteroid (3α,5α)3-Hydroxypregnan-20-one Inhibits Toll-like-4 Receptor Activation and Pro-inflammatory Signaling in Macrophages and Brain. Sci Rep. 2019 Feb 4;9(1):1220. doi: 10.1038/s41598-018-37409-6. PMID: 30718548; PMCID: PMC6362084.
  5. Morrow AL, Boero G, Balan I. Emerging evidence for endogenous neurosteroid modulation of pro-inflammatory and anti-inflammatory pathways that impact neuropsychiatric disease. Neurosci Biobehav Rev. 2024 Mar;158:105558. doi: 10.1016/j.neubiorev.2024.105558. Epub 2024 Jan 19. PMID: 38244954.