Prematurity as a factor of damaged child development



At present time prematurity is the main reason for disability in children, which can be exemplified by the fact that 2/3 of educatees of children' homes for blind and deaf are preterm children. The most drastic consequences of prematurity is cerebral palsy with spastic diplegia; blindness or poor vision as a result of retina detachment; auditory inefficiency connected with the nerve deafness, decline in general cognitive and speech development; difficulties in coordination and planning serial operations; psycho-emotional impairments like autism. The distinctive features of appearance (failure to thrive, microcephalism with deformation of the shape of the head) and behavior (stereotyped movements, lack in initiative purposeful activity) make these children recognizable and let us talk about naturally determined set of impairments connected with the main reason — prematurity. The article regards the influence of preterm birth on child's nervous system and it's remote effect on his/her psychic development.

General Information

Keywords: prenatal development of the brain, prematurity, multiple developmental impairments in children

Journal rubric: Medical Psychology

Article type: review article

For citation: Chuhutova G.G. Prematurity as a factor of damaged child development [Elektronnyi resurs]. Sovremennaia zarubezhnaia psikhologiia = Journal of Modern Foreign Psychology, 2014. Vol. 3, no. 1, pp. 72–85. (In Russ., аbstr. in Engl.)


  1. Basilova T. A. Ob izmenenii etologii i struktury narushenii pri slepoglukhote za 35 let nabliudenii [On the change of ethology and patterns of violations in deafblindness in 35 years of observations] // Zhurnal psikhicheskogo zdorov'ia detei i podrostkov [Journal of mental health of children and adolescents]. 2011. T.11, №. 2. pp. 12—20.
  2. Vasil'eva M. Iu. Nedonoshennye deti: predskazuemoe otstavanie ili operezhaiushchee razvitie? [Preterm infants: a predictable lag or advanced development?] // Chetvertaia mezhdunarodnaia konferentsiia po kognitivnoi nauke [Fourth International Conference on Cognitive Science: Abstracts]: Tezisy dokladov: V 2 t. Tomsk, 22—26 iiunia 2010 g. Tomsk: Tomskii gosudarstvennyi universitet. 2010. T. 1. pp. 188—190.
  3. Osobennosti razvitiia psikhicheskikh funktsii u gluboko nedonoshennykh mladentsev [Peculiarities of mental functions in very preterm infants] / Burdukova Iu. A., Stroganova T. A., Posikera I. N., Tsetlin M. M. // Sb. materialov "Pervoi rossiiskoi konferentsii po kognitivnoi nauke" [Proc. materials "First Russian Conference on Cognitive Science"]. 2004. pp. 42—44.
  4. Shabalov N. P. Neonatologiia [Neonatology]: Uchebn. posobie: V 2 t. T. 1. 3-e izd., ispr. i dop. Moscow: MEDpress-inform, 2004. 608 p.
  5. Abnormal orbitofrontal development due to prematurity / Gimenez M. Junque C., Vendrell P., Narberhaus A., Bargallo N., Botet F., Mercader J. M. Neurology. 2006. Vol. 67, no. 10. pp. 1818—1822.
  6. Alyward G. P. Outcome studies of low birth weight infants published in the last decade: A meta-analysis / Alyward G. P., Pfeiffer S. I., Wright A., Verhulst S. J. // Journal of Pediatrics. 1989. Vol. 115. no. 4. pp. 515—520.
  7. Andersen S. L. Trajectories of brain development: point of vulnerability or window of opportunity? // Neuroscience & Biobehavioral Reviews, 2003. Vol. 27, no. 1. pp. 3—18.
  8. Anderson P. J., Doyle L. W. Cognitive and educational deficits in children born extremely preterm // Seminars in perinatology. WB Saunders, 2008. Vol. 32, no. 1. pp. 51—58.
  9. Arpino C. Brain damage in preterm infants: Etiological pathways / Arpino C., D'Argenzio L., Ticconi C., Di Paolo A., Stellin V., Lopez L., Curatolo P. Annali dell'Istituto superiore di sanita. 2004. Vol. 41, no. 2. pp. 229—237.
  10. Bom B. Developmental risks and protective factors for influencing cognitive outcome at 5½ of age in very low birthweight children / Bom B., Katz-Salamon M., Smedler A. C., Lagercrantz H., Forssberg H. Developmental Medicine and Child Neurology. 2002. Vol. 44. pp. 508—516.
  11. Brain injury in very preterm children and neurosensory and cognitive disabilities during childhood: The EPIPAGE cohort study / Marret S., Marchand-Martin L., Picaud J. C., Hascoet J. M., Arnaud C., Roze J. C., EPIPAGE Study Group // PloS one, 2013. Vol. 8. no. 5.
  12. Brain maturation of preterm newborn babies: new insights / Ramenghi L. A., Fumagalli M., Bassi L., Groppo M., De Carli A., Fanaro S., Mosca F. Journal of pediatric gastroenterology and nutrition. 2007. Vol. 45. pp. 143—146.
  13. Burstein J., Papile L. A., Burstein R. Intraventricular hemorrhage and hydrocephalus in premature newborns: A prospective study with CT //American Journal of Roentgenology. 1979. Vol. 132. no. 4. pp. 631—635.
  14. Chang H. H. Preventing preterm births: Analysis of trends and potential reductions with interventions in 39 countries with very high human development index / Chang H. H., Larson J., Blencowe H., Spong C. Y., Howson C. P., Cairns-Smith S., Lawn J. E. The Lancet. 2013. Vol. 381 (9862). pp. 223—234.
  15. Children born prematurely have atypical Sensory Profiles / Wickremasinghe A. C., Rogers E. E., Johnson B. C., Shen A., Barkovich A. J., Marco E. J. // Journal of Perinatology, 2013. Vol. 33. no. 8. pp. 631—635.
  16. Contribution of Brain Size to IQ and Educational Underperformance in Extremely Preterm Adolescents [Electronic resource] / Cheong J. L., Anderson P. J., Roberts G., Burnett A. C., Lee K. J., Thompson D. K., Doyle L. W. // PloS one. 2013. Vol. 8 no. 10. URL: (Accessed: 15.01.2014).
  17. Dammann O., Leviton A. Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn // Pediatric research. 1997. Vol. 42, no. 1. pp. 1—8.
  18. Decreased regional brain volume and cognitive impairment in preterm children at low risk / Soria-Pastor S., Padilla N., Zubiaurre-Elorza L., Ibarretxe-Bilbao N., Botet F., Costas-Moragas C., Junque C. // Pediatrics. 2009. Vol. 124. no. 6. pp. 1161—1170.
  19. Derleth D. P. Blood pressure in low birth weight infants after dexamethasone // European journal of pediatrics. 1994. Vol. 153, no. 3. pp. 211—211.
  20. Dewey D. Parents rating of everyday cognitive abilities in very low birth weight children / Dewey D., Crawford S. G., Creighton D. E., Sauve R. S. // Journal of Developmental and Behavior Pediatrics. 2000. Vol. 21, no. 3. pp. 37—43.
  21. Epidemiology and causes of preterm birth / Goldenberg R. L., Culhane J. F., Iams J. D., Romero R. // The lancet. 2008. Vol. 371 (9606). pp. 75—84.
  22. Hack M. Adult outcomes of preterm children // Journal of Developmental & Behavioral Pediatrics, 2009. Vol. 30. no. 5. pp. 460—470.
  23. Hippocampal gray matter reduction associates with memory deficits in adolescents with history of prematurity / Gimenez M., Junque C., Narberhaus A., Caldu X., Salgado-Pineda P., Bargallo N., Botet F. // Neuroimage. 2004. Vol. 23. no. 3. pp. 869—877.
  24. Inder T. E. Abnormal cerebral structure is present at term in premature infants / Inder T. E. Warfield S. K., Wang H., Huppi P. S., Volpe J. J. // Pediatrics. 2005. Vol. 115. no. 2. pp. 286—294.
  25. Luciana M. Cognitive development in children born preterm: Implications for theories of brain plasticity following early injury // Development and psychopathology. 2003. Vol. 15. no. 4. pp. 1017—1047.
  26. Marin-Padilla M. Developmental neuropathology and impact of perinatal brain damage: White matter lesions of the neocortex // Journal of Neuropathology & Experimental Neurology. 1997. Vol. 56. no. 3. pp. 219—235.
  27. Maunu J. The Vulnerable Brain and Very Preterm Infants-Findings from the PIPARI-Study. Turku: University of Turku, 2010. 88 p.
  28. McGrath M. M. Longitudinal neurologic follow-up in neonatal intensive care unit survivors with various neonatal morbidities / McGrath M. M., Sullivan M. C., Lester B. M. Oh. W. // Pediatrics. 2000. Vol. 106. no. 6. pp. 1397—1405.
  29. Menon R. Spontaneous preterm birth, a clinical dilemma: Etiologic, pathophysiologic and genetic heterogeneities and racial disparity // Acta obstetricia et gynecologica Scandinavica. 2008. Vol. 87 no. 6. pp. 590—600.
  30. Muglia L. J., Katz M. The enigma of spontaneous preterm birth // The New England Journal of Medicine. 2010. Vol. 362. no. 6. pp. 529—535.
  31. Neurodevelopmental outcome at 5 years of age of a national cohort of extremely low birth weight infants who were born in 1996—1997 / Mikkola K., Ritari N., Tommiska V., Salokorpi T., Lehtonen L., Tammela O., Fellman V. // Pediatrics. 2005. Vol.116. no. 6. pp. 1391—1400.
  32. Neurogenesis continues in the third trimester of pregnancy and is suppressed by premature birth / Malik S., Vinukond, G., Vose L. R., Diamond D., Bhimavarapu B. B., Hu F., Ballabh P. // The Journal of Neuroscience, 2013. Vol. 33(2), pp. 411—423.
  33. Patton G. C. Prematurity at birth and adolescent depressive disorder / Patton G. C., Coffey C., Carlin J. B., Olsson C. A., Morley R. The British Journal of Psychiatry, 2004. Vol. 184 (5). pp. 446—447.
  34. Plunkett J., Muglia L. J. Genetic contributions to preterm birth: implications from epidemiological and genetic association studies // Annals of medicine. 2008. Vol. 40. no. 3. pp. 167—179.
  35. Stephens B. E., Vohr B. R. Neurodevelopmental outcome of the premature infant // Pediatric Clinics of North America. 2009. Vol. 56. no. 3. pp. 631—646.
  36. Volpe J. J. Brain injury in the premature infant-from pathogenesis to prevention // Brain and development. 1997. Vol. 19. no. 8. pp. 519—534.
  37. Witelson S. F., Nowakowski R. S. Left out axons make men right: A hypothesis for origin of handedness and functional asymmetry. Neuropsychology. 1991. Vol. 29. no. 4. pp. 327—333.
  38. Word Health Organization. WHO: Recommended definitions, terminology and format for statistical tables related to the perinatal period and use of a new certificate for cause of perinatal deaths // Acta Obstetricia et Gynecologica Scandinavica. 1977. Vol. 56. no. 3. pp. 247—253.

Information About the Authors

Galina G. Chuhutova, Psychologist, Sergiev Posad Children's Home for the Deafblind of the Ministry of Labor and Social Protection of the Population of Russia, Sergiev Posad, Russia, e-mail:



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