Genetic Mechanisms of Mental Disturbances: Chromosomal and Genomic Disorders

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Abstract

Currently, it is well known that genetic anomalies significantly contribute to pathogenesis of different mental disturbances, including such diseases as mental retardation, autism, schizophrenia and Alzheimer’s disease. More precisely, up to 50% of cases of these diseases can be associated with gene, chromosomal and genomic mutations. In this context, providing for medical and psychological help at modern level for individuals affected by these diseases would be incomplete without application of newly introduced methods for genome analysis to diagnose and to identify mechanisms of neuropsychiatric disorders. Here, a brief overview of current advances in analyses of genetic mechanisms of mental disturbances and developments in diagnosis of chromosomal and genomic disorders are given.

General Information

Keywords: autism, Alzheimer’s disease, genome, DNA, mental retardation, chromosomal abnormalities, schizophrenia.

Journal rubric: Clinical and Special Psychology

Article type: scientific article

For citation: Yurov I.Y., Vorsanova S.G., Yurov Y.B. Genetic Mechanisms of Mental Disturbances: Chromosomal and Genomic Disorders [Elektronnyi resurs]. Psikhologicheskaya nauka i obrazovanie psyedu.ru [Psychological Science and Education psyedu.ru], 2010. Vol. 2, no. 5 (In Russ., аbstr. in Engl.)

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Information About the Authors

Ivan Y. Yurov, Doctor of Biology, leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents”, Moscow State University of psychology and education (MSUPE), Professor of the Russian Academy of Natural Sciences, leading researcher at the RAMS Scientific Center for Mental Health of the Russian Academy of Medical Sciences., Moscow, Russia, e-mail: ivan_iourov@yahoo.com

Svetlana G. Vorsanova, Doctor of Biology, professor, head of laboratory Institute of pediatrics and pediatric surgery, Rosmedtehnologii, Moscow State University of psychology and education (MSUPE), Leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents”, Moscow State University of Psychology and Education, Moscow, Russia, e-mail: svorsanova@mail.ru

Yuriy B. Yurov, Doctor of Biology, professor, head of laboratory, Research center of mental health, Moscow State University of Psychology and Education Leading researcher of the scientific and educational center “Neurobiological diagnosis of hereditary diseases in children and adolescents”, Moscow, Russia, e-mail: y_yurov@yahoo.com

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