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  Previous issue (2019. Vol. 17, no. 3)

Autism and Developmental Disorders

Publisher: Moscow State University of Psychology and Education

ISSN (printed version): 1994-1617

ISSN (online): 2413-4317

DOI: https://doi.org/10.17759/autdd

License: CC BY-NC 4.0

Started in 2003

Published quarterly

Free of fees
Open Access Journal

 

Autism Spectrum Disorders — in Search of Mechanistic Biomarkers 572

Rabbani N., PhD, Reader of Experimental Systems Biology, Warwick Medical School and Zeeman Institute for Systems Biology & Infectious Disease Epidemiology Research; University of Warwick, Coventry, Great Britain, N.Rabbani@warwick.ac.uk
Thornalley P.J., PhD, Director, Diabetes Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University; Qatar Foundation, Doha, Qatar, pthornalley@hbku.edu.qa
Abstract
Autism spectrum disorders are a group of neuropsychiatric conditions of increasing prevalence. They are initially detected in early development of children. Diagnosis is currently made on the basis of clinical behaviour and cognition. Improvements in accuracy, timeliness and access to diagnosis to help manage the condition is high on the agenda of the autistic communities. A blood test may help for early-stage detection of autism spectrum disorders to focus support where required — particularly when symptoms are most challenging. This article discusses briefly the scientific basis of diagnosis of autism spectrum disorders and recent emergence of candidate blood tests for autism. We conclude that further validation and improvements in understanding of autism spectrum disorders are required to provide the scientific basis and classifier characteristics for accurate and reliable diagnosis by clinical chemistry blood test.

Keywords: blood test, diagnosis, proteomics, autistic adults, delayed diagnosis

Column: (null)

DOI: https://doi.org/10.17759/autdd.2019170103

For Reference

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