Profiles of Cognitive Deficits in Paranoid Schizophrenia and Schizotypal Disorder

1958

Abstract

The article is devoted to the search for more accurate psycho-diagnostic methods and assessment tools for determining the degree of cognitive deficits in patients with schizophrenic disorders. The concepts of "cognitive deficits" and "cognitive profile", understood as the ratio of intact and damaged components of cognitive processes and their schematic representation are discussed. The authors substantiate the need for a clear gradation of cognitive impairments in schizophrenia, development of universal translation algorithms of traditional qualitative results (meaningful) analysis of violations of cognitive activity in quantitative indicators. The article is based on the results of experimental psychological study. The investigation involved 128 patients: 76 people with Paranoid schizophrenia (F20 according to ICD-10) and 52 persons with Schizotypal disorder (F21 according to ICD-10). To assess the cognitive deficit, both traditional domestic methods and foreign tests, rarely used in the practice of a medical psychologist were conducted. The study analyzed the difference in cognitive tests performance between groups of patients with several types of schizophrenia and with different disease duration (up to 5 years and more). On the basis of quantitative data, a "cognitive profile" was lined for each disease. As a result, different variants of cognitive deficits, depending on the shape and course of the disease have been identified. The structure and dynamics of the cognitive deficits associated with schizophrenia and various forms depending on the different duration of the disease is described in detail. Also cognitive profiles compiled on this basis.

General Information

Keywords: schizophrenia, cognitive deficits, cognitive violation, cognitive profile

Journal rubric: Empirical Research

Article type: scientific article

DOI: https://doi.org/10.17759/cpse.2017060106

For citation: Lebedeva G., Isaeva E.R. Profiles of Cognitive Deficits in Paranoid Schizophrenia and Schizotypal Disorder [Elektronnyi resurs]. Klinicheskaia i spetsial'naia psikhologiia = Clinical Psychology and Special Education, 2017. Vol. 6, no. 1, pp. 79–94. DOI: 10.17759/cpse.2017060106. (In Russ., аbstr. in Engl.)

References

  1. Verbenko V.A. Neyrokognitivnye rasstroystva pri shizofrenii [Neurocognitive disorders in schizophrenia]. Simferopol': OOO DIAYPI, 2007. 308 p.
  2. Voytenko R.M., Sakovskaya V.G., Filippova M.P. Izmeneniya psikhicheskikh protsessov i metody ikh issledovaniya. Znachenie v MSE. Uchebno-metodicheskoe posobie [Changes in mental processes and methods of their study. Meaning in ITU. Educational handbook]. Saint-Petersburg: Aysing, 2014. 44 p.
  3. Voytenko R.M. Sotsial'naya psikhiatriya s osnovami mediko-sotsial'noy ekspertizy i reabilitologii: ruk-vo dlya vrachey i klinicheskikh psikhologov [Social psychiatry with the basics of medical and social expertise and rehabilitation: a hand-for physicians and clinical psychologists]. Saint-Petersburg, 2011. 192 p.
  4. Dorodnova A. S. Kliniko–sotsial'nye i organizatsionnye aspekty pomoshchi bol'nym shizofreniey i rasstroystvami shizofrenicheskogo spektra s pervymi psikhoticheskimi epizodami: dis... kand.med.nauk [Clinical, social and organizational aspects of helping patients with schizophrenia and disorders of the schizophrenic spectrum with the first psychotic episodes: Phd Thesis (Medicine)]. Moscow, 2006. 175 p.
  5. Zaytseva Yu.S., Korsakova N.K. Dinamika neyrokognitivnogo defitsita u patsientov s razlichnoy stepen'yu progredientnosti shizofrenii pri pervykh pristupakh i v techenie 5-letnego katamneza [Dynamics of neurocognitive deficits in patients with different degrees of schizophrenia progression during first attacks and during 5-year-old catamnesis]. Sotsial'naya i klinicheskaya psikhiatriya [Social and Clinical Psychiatry], 2008, vol. 18, no. 2, pp. 15–25.
  6. Kondrat'ev F.V. Sud'ba bol'nykh shizofreniey (kliniko-sotsial'nyy i sudebno-psikhiatricheskiy aspekty) [The fate of patients with schizophrenia (clinical and social and forensic psychiatric aspects)]. Moscow: Yustitsinform, 2010. 402 p.
  7. Lebedeva G.G. Varianty kognitivnogo defitsita v sravnenii s klinicheskimi kharakteristikami u patsientov s paranoidnoy shizofreniey [Variants of cognitive deficits in comparison with clinical characteristics in patients with paranoid schizophrenia] [Electronic resource]. In A.I. Andreev, A.V. Andriyanov, E.A. Antipov (Eds.) Materialy Mezhdunarodnogo molodezhnogo nauchnogo foruma «Lomonosov-2015» [Proceedings of the International Youth Scientific Forum "Lomonosov-2015"]. Moscow: MAKS Press, 2015. URL: http://lomonosov-su.ru/archive/Lomonosov_2015/data/section_22_6911.htm (Accessed: 23.03.2017).
  8. Lebedeva G.G. Isaeva E.R. Varianty kognitivnogo defitsita v zavisimosti ot klinicheskikh kharakteristik zabolevaniya u patsientov s paranoidnoy shizofreniey [Variants of cognitive deficiency depending on the clinical characteristics of the disease in patients with paranoid schizophrenia]. Uchenye zapiski Sankt-Peterburgskogo gosudarstvennogo meditsinskogo universiteta im. akademika I.P.Pavlova [The Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University], 2015, vol. 22, no. 1, pp. 51–54.
  9. Lebedeva G.G., Isaeva E.R., Stepanova A.V. Kognitivnyy defitsit pri paranoidnoy shizofrenii i shizotipicheskom rasstroystve: sravnitel'noe issledovanie kognitivnykh narusheniy [Cognitive deficiency in paranoid schizophrenia and schizotypic disorder: a comparative study of cognitive impairment]. Vestnik. Tomskogo gos. ped. un-ta [Bulletin of Tomsk State Pedagogical University], 2013, Iss. 5, pp. 155–160.
  10. Magomedova M.V. Sootnoshenie sotsial'nogo funktsionirovaniyai neyrokognitivnogo defitsita u bol'nykh shizofreniey i shizoaffektivnym rasstroystvom na rannem i otdalennom etape bolezni. Diss. kand. med. nauk [Correlation of social functioning and neurocognitive deficiency in patients with schizophrenia and schizoaffective disorder at an early and distant stage of the disease: PhD (Medicine) diss. Moscow, 2003. 142 p.
  11. Minutko V.L. Shizofreniya [Schizophrenia]. Kursk: “Kursk”, 2009. 688 p.
  12. Mukhitova Yu.V. Kognitivnye disfunktsii pri raznoy stepeni vyrazhennosti psikhicheskogo defekta u bol'nykh shizofreniey: diss. ... kand. psikhol. nauk [Cognitive dysfunctions with different degrees of severity of mental defect in patients with schizophrenia. PhD (Psychology) diss.]. Saint-Petersburg, 2013. 158 p.
  13. Stepanova A.V., Isaeva E.R., Kotsyubinskiĭ A.P., Lebedeva G.G. Sravnitel'nyy̆ analiz kognitivnykh disfunktsiĭ u patsientov s paranoidnoĭ shizofreniey i shizotipicheskim rasstroystvom [Comparative analysis of cognitive dysfunctions in patients with paranoid schizophrenia and schizotypic disorder]. Obozrenie psikhiatrii i meditsinskoy psikhologii im. V.M. Bekhtereva [Bekhterev Review of Psychiatry and Medical Psychology], 2014, no. 4,
    pp. 62–67.
  14. Shmukler A.B. Strukturno-funktsional'naya rassoglasovannost' razlichnykh otdelov golovnogo mozga pri shizofrenii: rol' integrativnoy pertseptsii [Structural and functional mismatch of different divisions of the brain in schizophrenia: the role of integrative perception]. Sotsial'naya i klinicheskaya psikhiatriya [Social and Clinical Psychiatry], 2010, vol. 20, no. 3, pp. 86–95.
  15. Shmukler A.B., Gurovich I.Ya., Papsuev O.O. Dinamika neyrokognitivnykh i sotsial'no-kognitivnykh funktsiy pri shizofrenii [Dynamics of neurocognitive and socio-cognitive functions in schizophrenia]. In Z.I. Kekelidze (ed.) Sbornik materialov VI Natsional'nogo kongressa po sotsial'noy psikhiatrii i narkologii [Proceedings of VI National Congress on Social Psychiatry and Addiction]. Moscow: Publ. of FGBU “FMITsPN im.
    V.P. Serbskogo”, 2016, pp. 104–105.
  16. Gold J.M., Harvey P.D. Cognitive deficit in schizophrenia. Psychiatric Clinics of North America, 1993, vol. 16, pp. 259–312.
  17. Keefe R.S., Eesley S.E. Neurocognition in schizophrenia. In B.J. Sadock, V.A. Sadock,
    P. Ruiz (Eds.) Kaplan&Sadock`s comprehensive textbook of psychiatry: 9th ed. Philadelphia, PA: Lippincott Williams&Wilkins, 2009, pp. 1531–1541.
  18. Savla G.N., Moore D.J., Palmer B.W. Cognitive functioning. In K.T. Mueser, D.V. Jeste (Eds.) Clinical handbook of schizophrenia. New York, NY: Guilford Press, 2008, pp. 91–99.
  19. Saykin A.J. Gur R.C., Gur R.E., et. al. Neuropsychological function in schizophrenia: selective impairment in memory and learning. Archives of General Psychiatry, 1991, vol. 48, pp. 618–624.
  20. Wykes T., Reeder C. Cognitive Remediation therapy for schizophrenia. London: Routledge, 2005. 315 p.

Information About the Authors

Gul'fija Lebedeva, Associate Professor, chair of General and Medical Psychology, Federal State Budgetary Educational Institution of Higher Education “Academician I.P. Pavlov First St. Petersburg State Medical University”, St.Petersburg, Russia, e-mail: lebedeva2512@gmail.com

Elena R. Isaeva, Doctor of Psychology, Professor, Head of the Department of Psychology and Clinical Psychology, The First Pavlov State Medical University of St. Petersburg, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-7731-7693, e-mail: isajeva@yandex.ru

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