Features of Visual Information Processing in Patients with Schizophrenia in the Early Stages

189

Abstract

We performed the analysis of electrophysiological markers of visual information processing in schizophrenia. The relevance of this work is determined by the advantages of combining of the method of cognitive visual evoked potentials and the method of spatial-frequency filtering of images with different semantics in order to detect disorders. This method allows assessing of the functional state of the visual system in the early stages of cognitive impairment, based on the objective electrophysiological methods. We studied the nature of changes in the amplitudes of the components of evoked potentials in response to the presentation of a combination of stimuli with different spatial-frequency and semantic characteristics (objects of animate and inanimate nature) in patients with schizophrenia in the early stages. The obtained data indicated a predominant decrease in the activity of the "high-frequency" parvo system, which manifests itself in a perception disorder and the abnormality of processing of small images and their details. Also, we obtained data in patients with schizophrenia that signifies an abnormality of the involuntary classification of images of objects of animate and inanimate nature. The obtained result is important for the understanding of the features of visual information processing in patients with schizophrenia in the early stages of the disease and the development of methods of cognitive impairments measuring.

General Information

Keywords: cognitive visual evoked potentials, low and high spatial frequency, stimuli of animate and inanimate nature, schizophrenia

Journal rubric: Psychophysiology

Article type: scientific article

DOI: https://doi.org/10.17759/exppsy.2023160103

Funding. The work was supported by the State Program 47 of the State Enterprise "Scientific and Technological Development of the Russian Federation" (2019-2030), topic 0134-2019-0006 (section 63.3).

Received: 26.01.2022

Accepted:

For citation: Murav'eva S.V., Shchemeleva O.V., Lebedev V.S., Vershinina E.A. Features of Visual Information Processing in Patients with Schizophrenia in the Early Stages. Eksperimental'naâ psihologiâ = Experimental Psychology (Russia), 2023. Vol. 16, no. 1, pp. 43–61. DOI: 10.17759/exppsy.2023160103. (In Russ., аbstr. in Engl.)

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Information About the Authors

Svetlana V. Murav'eva, PhD in Medicine, Associate Researcher of the Laboratory of Physiology , Pavlov Institute of Physiology, Russian Academy of Sciences, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0003-3901-4138, e-mail: mlanka@freemail.ru

Olga V. Shchemeleva, Researcher, Laboratory of Physiology of Vision, Pavlov Institute of Physiology, Russian Academy of Sciences, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-2777-6373, e-mail: oshchemeleva@gmail.com

Vladislav S. Lebedev, PhD Student, Laboratory of Physiology of Vision, Pavlov Institute of Physiology, Russian Academy of Sciences, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-6715-4552, e-mail: vlad840708@yandex.ru

Elena A. Vershinina, PhD in Biology, Senior Researcher, Laboratory of Information Technologies and Mathematical Modeling, Pavlov Institute of Physiology, Russian Academy of Sciences, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-8873-4409, e-mail: ver_elen@mail.ru

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