High-Functioning Autism and its Understanding in Modern Literature

4

Abstract

Objective. Among autism spectrum disorders (ASD), high functional autism (HFA) is not considered a separate nosological entity. However, a number of foreign studies have shown that 10% of people with ASD are diagnosed with HFA. We discuss the characteristics of HFA as well as its differences from other ASD subgroups. The article also summarizes the current state of research on the HFA issue. A clearer understanding of both psychology and neurophysiology of high-functioning autism will help ensure accurate diagnosis, avoiding errors in therapy planning and support.

Methods. We reviewed literature sources in the PubMed, MedLine, and Scientific Electronic Library databases. The main search terms were: high-functioning autism, HFA, Asperger’s syndrome, autism spectrum disorders (ASD), diagnosis and speech disorders. Forty-two articles by foreign and domestic specialists were included in the analysis.

Results. The developmental profile of individuals with high-functioning autism differs from that of individuals with autism and cognitive or speech impairments. It is characterized by a distinctive style of social interaction and a higher level of speech and cognitive development. A high level of intelligence helps people with HFA master social rules and adapt more effectively.

Conclusions. Social impairments in individuals with high-functioning autism are difficult to identify in early childhood, partly due to the lack of developed diagnostic tools. Therefore, there is a need for more careful assessment of children suspected of having high-functioning autism, as well as the development of reliable, sensitive assessment tools for follow-up therapy and support.

General Information

Keywords: high-functioning autism (HFA); Asperger syndrome; autism spectrum disorders (ASD); diagnostics; speech disorders; EEG; ASD neurobiology

Journal rubric: Research of ASD

Article type: scientific article

DOI: https://doi.org/10.17759/autdd.2024220401

Received: 06.02.2024

Accepted:

For citation: Danilina K.K., Salimova K.R. High-Functioning Autism and its Understanding in Modern Literature. Autizm i narusheniya razvitiya = Autism and Developmental Disorders, 2024. Vol. 22, no. 4, pp. 4–12. DOI: 10.17759/autdd.2024220401. (In Russ., аbstr. in Engl.)

References

  1. Bashina M. O sindrome rannego detskogo autizma Kannera [On the syndrome of infantile autism Kanner]. Zhurnal nevrologii i psixiatrii im S.S. Korsakova = S.S. Korsakov Journal of Neurology and Psychiatry. 1974. vol. 74. no. 10. pp. 1538— 1542.
  2. Gorbachevskaya N.L., Mamokhina U.A., Vershinina N.V. et al. Osobennosti spektral’nykh kharakteristik EEG u lits s rasstroistvami autisticheskogo spektra [Specificities of EEG spectral characteristics in individuals with autism spectrum disorders]. Psikhiatriya = Psychiatry (Moscow), 2018, no. 2, pp. 48—54.
  3. Iovchuk N.M., Severnyi A.A. Problemy diagnostiki i korrektsii autizma u detei (na primere sindroma Aspergera) [Problems of diagnosis and correction of autism in children (on the example of Asperger’s syndrome)]. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova = S. Korsakov Journal of Neurology and Psychiatry, 2014, vol. 114, no. 1, pt. 2, 15—19.
  4. MKB-11 | Mezhdunarodnaya klassifikatsiya boleznei 11-go peresmotra [ICD-11 | International Classification of Diseases 11th Revision]: [Web resource]. URL: https://icd11.ru (Accessed 12.02.2024).
  5. Sorokin A.B., Davydova E.Yu., Samarina L.V. et al. Standardized Diagnostic Instruments for Autism Spectrum Disorders: the Use of ADOS-2 and ADI-R. Autizm i narusheniya razvitiya = Autism and Developmental Disorders (Russia), 2021, 19, no. 1, pp. 12—24. DOI:10.17759/autdd.2021190102
  6. Tyushkevich S.A., Mamokhina U.A., Danilina K.K. et al. On the mechanisms of the occurrence of autism spectrum disorders: a family case Autizm i narusheniya razvitiya = Autism and Developmental Disorders (Russia), 2020, vol. 18, no. 2, pp. 32—40. DOI:10.17759/autdd.2020180205
  7. Chizh D.I., Petrova E.V., Muzhikov V.S. et al. Osobennosti EEG-diagnostiki u detei s rasstroistvami autisticheskogo spektra [Pecularities of EEG diagnostics in children with autism spectrum disorders]. Ul’yanovskii mediko- biologicheskii zhurnal = Ulyanovsk Medico-Biological Journal, 2021, 2, pp. 69—82. DOI:10.34014/2227-1848- 2021-2-69-82
  8. Asperger H. Die ‚aunstisehen Psychopathen‘ im Kindesalter // Archiv fur psychiatrie und 1944. Vol. 117. pp. 76—136.
  9. Blumberg S.J., Bramlett M.D., Kogan M.D. et al. Changes in prevalence of parent-reported autism spectrum disorder in school-aged US Children: 2007 to 2011—2012. National Health Statistics Reports. 2013. Vol. 65. pp. 1—11.
  10. Campbell Diagnostic assessment of Asperger’s disorder: a review of five third-party rating scales. Journal of Autism and Developmental Disorders. 2005. Vol. 35. pp. 25—35. DOI:10.1007/s10803-004-1028-4
  11. Cederlund , Gillberg C. One hundred males with Asperger syndrome: A clinical study of background and associated factors. Developmental Medicine and Child Neurology. 2004. Vol. 46. No. 10. pp. 652—660. DOI:10.1017/ s0012162204001100
  12. Clarke A.R., Barry R.J., Indraratna A. et al. EEG activity in children with Asperger’s Syndrome. Clinical Neurophysiology. Vol. 127. no 1. pp. 442—451. DOI:10.1016/j.clinph.2015.05.015
  13. Gold , Faust M. Right hemisphere dysfunction and metaphor comprehension in young adults with Asperger syndrome. Journal of Autism and Developmental Disorders. 2010. Vol. 40. pp. 800—811. DOI:10.1007/s10803-009-0930-1
  14. Hippler, Klicpera C. A retrospective analysis of the clinical case records of autistic psychopaths’ diagnosed by Hans Asperger and his team at the University Children’s Hospital, Vienna. Philosophical Transactions of the Royal Society of London: Series B: Biological Sciences. 2003. Vol. 358. no. 1430. Pp. 291—301. DOI:10.1098/ rstb.2002.1197
  15. Howlin Outcome in high-functioning adults with autism with and without early language de- lays: implications for the differentiation between autism and Asperger syndrome. J. Autism Dev. Disord. 2003. V. 33. No. 1. Pp. 3—13. DOI:10.1023/a:1022270118899
  16. Jin W.-Y., Wu L.-L., Hu L.-F. et al. Intelligence profiles and adaptive behaviors of high-functioning autism spectrum disorder and developmental speech and language Frontiers in Pediatrics. 2023. Vol. 10. Article no. 972643. 10 p. DOI:10.3389/fped.2022.972643
  17. Jung-Beeman Bilateral brain processes for comprehending natural language. Trends in Cognitive Sciences. 2005. Vol. 9. no. 11. Pp. 512—518. DOI:10.1016/j.tics.2005.09.009
  18. Kanner Autistic disturbances of affective contact // Nervous Child. 1943. Vol. 2. pp. 217—250.
  19. Khouzam R., El-Gabalawi F., Pirwani N. et al. Asperger’s disorder: a review of its diagnosis and treatment. Comprehensive Psychiatry. 2004. Vol. 45. no. 3. pp. 184—191. DOI:10.1016/j.comppsych.2004.02.004
  20. Klin A. Autism and Asperger syndrome: an overview. Bras. Psiquiatr. 2006. V. 28. pp. 3—11. DOI:10.1590/s1516- 44462006000500002
  21. Klin A., Volkmar F.R., Sparrow S.S. et.al. Validity and neuropsychological characterization of Asperger syndrome: convergence with nonverbal learning disabilities syndrome. Child Psychol. Psychiatry. 1995. Vol. 36. No. 7. pp. 1127— 1140. DOI:10.1111/j.1469-7610.1995.tb01361.x
  22. Koumenidou , Kotzamanidou M., Panoutsakopoulos V. et al. The Long-Term Adaptations of a Combined Swimming and Aquatic Therapy Intervention in an Adult Person with High-Functioning Autism (Asperger’s Syndrome): A Case Study. Healthcare (Basel). 2023. V. 11. pp. 2986. doi:10.3390/healthcare11222986.
  23. Koyama T., Tachimori H., Osada H. et.al. Cognitive and symptom profiles in Asperger’s syndrome and high-functioning Psychiatry Clin. Neurosci. 2007. V. 61. no. 1. pp. 99—104. DOI:10.1111/j.1440-1819.2007.01617.x
  24. Lebersfeld B., Swanson M., Clesi C.D. et al. Systematic Review and Meta-Analysis of the Clinical Utility of the ADOS- 2 and the ADI-R in Diagnosing Autism Spectrum Disorders in Children. Journal of Autism and Developmental Disorders. 2021. Vol. 51. pp. 4101—4114. DOI:10.1007/s10803-020-04839-z
  25. Lee , Liang L., Hou W.K., et al. The Chinese “Reading the Mind in the Eyes” Test: A study with normal adults, and adults with Asperger syndrome/high-functioning autism. Asian J Psychiatr. 2023. V. 89. pp. 103785. doi:10.1016/j. ajp.2023.103785.
  26. Lotspeich L.J., Kwon H., Schumann C.M. et al. Investigation of neuroanatomical differences between autism and Asperger Archives Of General Psychiatry. 2004. Vol. 61. no. 3. pp. 291—298. DOI:10.1001/archpsyc.61.3.291
  27. Mahjouri, Lord C.E. What the DSM-5 portends for research, diagnosis, and treatment of autism spectrum disorders. Current Psychiatry Reports. 2012. Vol. 14. Pp. 739—747. DOI:10.1007/s11920-012-0327-2
  28. Martin I., McDonald S. An exploration of causes of non-literal language problems in individuals with Asperger Journal of Autism and Developmental Disorders. 2004. Vol. 34. pp. 311—328. DOI:10.1023/ b:jadd.0000029553.52889.15
  29. Mikami , Matsumoto H. Differentiation between childhood autism and Asperger’s syndrome. Ni- hon Rinsho. 2007. 65. pp. 487—491.
  30. Miller N., Ozonoff S. The external validity of Asperger disorder: lack of evidence from the domain of neuropsychology. Journal of Abnormal Psychology. 2000. Vol. 109. no. 2. Pp. 227—238
  31. .Nayate A., Tonge B.J., Bradshaw J.L. et al. Differentiation of high-functioning autism and Asperger’s disorder based on neuromotor Journal of Autism and Developmental Disorders. 2012. Vol. 42. pp. 707—717. DOI:10.1007/s10803- 011-1299-5
  32. Newschaffer С.J., Croen A., Daniels J. et al. The epidemiology of autism spectrum disorders. Annual Review of Public Health. 2007. Vol. 28. pp. 235—258. DOI:10.1146/annurev.publhealth.28.021406.144007
  33. Noterdaeme M., Wriedt E., Höhne C. Asperger’s syndrome and high-functioning autism: language, motor and cognitive Eur. Child Adolesc. Psychiatry. 2010. V. 19. pp. 475—481. DOI:10.1007/s00787-009-0057-0
  34. Rinehart N.J., Bradshaw J.L., Brereton A.V. et al. A clinical and neurobehavioural review of high-functioning autism and Asperger’s disorder. Australian & New Zealand Journal of Psychiatry. 2002. Vol. 36. no. 6. Pp. 762—770. DOI:10.1046/ 1440-1614.2002.01097.x
  35. Schweizer , Endres D., Dziobek I. et al. Psychosocial therapeutic approaches for high-functioning autistic adults. Frontiers in Psychiatry. 2024. Vol. 14. Article № 1265066. 10 p. DOI:10.3389/fpsyt.2023.1265066
  36. Sharma S., Woolfson L.M., Hunter S. Confusion and inconsistency in diagnosis of Asperger syndrome: a review of studies from 1981 to 2010. 2012. Vol. 16. no. 5. pp. 465—486. DOI:10.1177/1362361311411935
  37. Szatmari , Tuff L., Finlayson M.A. et al. Asperger’s syndrome and autism: neurocognitive aspects. J. Am. Acad. Child Adolesc. Psychiatry. 1990. V. 29. pp. 130—136. DOI:10.1097/00004583-199001000-00021
  38. Tarazi I., Sahli Z.T., Pleskow J. et al. Asperger’s syndrome: diagnosis, comorbidity and therapy. Expert Review of Neurotherapeutics. 2015. Vol. 15. no. 3. pp. 281—293. DOI:10.1586/14737175.2015.1009898
  39. Vicedo , Ilerbaig J. Autism in Baltimore, 1938—1943. Journal of Autism and Developmental Disorders. 2021. Vol. 51. 1157—1172. DOI:10.1007/s10803-020-04602-4
  40. Volkmar F, Klin A. Diagnostic issues in Asperger syndrome // Asperger syndrome / A. Klin, F.R. Volkmar, S.S. Sparrow (eds.). New York: Guilford Press. pp. 25—71. ISBN 1-57230-534-7.
  41. Wing Asperger’s syndrome: a clinical account. Psychological Medicine. 1981. Vol. 11. no. 1. Pp. 115—129. DOI:10.1017/ s0033291700053332
  42. Zarokanellou V., Papanikolaou K., Tafiadis D. et al. Qualitative analysis of verbal fluency in school-age children with high-functioning autism spectrum disorders: Associations with age and Applied Neuropsychology: Child. 2023. Vol. 12. no. 3. pp. 235—244. DOI:10.1080/21622965.2022.2090255

Information About the Authors

Kamilla K. Danilina, Researcher, Research and Clinical Center of Pediatric psychoneurology of Moscow Department of Public Health, Junior Researcher, Scientific laboratory, Federal Resource Center for Organization of Comprehensive Support to Childrenwith ASD, Moscow State University of Psychology & Education, Moscow, Russia, ORCID: https://orcid.org/0000-0002-0396-2884, e-mail: d-kk@mail.ru

Ksenia R. Salimova, Research Fellow of the Laboratory of Comprehensive Language Research in Children with Autism & Developmental Disorders, Moscow State University of Psychology & Education, Moscow, Russia, ORCID: https://orcid.org/0000-0001-6328-001X, e-mail: ksalimova@yandex.ru

Metrics

Views

Total: 35
Previous month: 30
Current month: 5

Downloads

Total: 4
Previous month: 3
Current month: 1