Regulatory Disorders in Adolescents with Hepatic Encephalopathy

The relevance of the study is due to the need to study the regulatory functions of adolescents with portal hypertension, which is accompanied by the development of a generalized intoxication effect on the nervous system affecting the cortical structures of the prefrontal parts of the brain. Objective: to study the specifics of prognostic regulation in adolescents with hepatic encephalopathy with portal hypertension. Materials and methods: the total sample size is 60 adolescents. The experimental group (EG) included adolescents in the number of 30 people (14 men; 16 women) with a diagnosis established by a gastroenterologist K76.6 "Portal hypertension" according to ICD-10. The control group (KG) included 30 respondents (14 men; 16 women) with a normative somatic status. The experimental and control groups were equalized by gender, age and social status. The empirical study included motivation, instruction, and psychological examination with the use of neurocognitive and test methods for assessing regulation: The Line Tracing Test, Digit-symbol Test, Number Connection Test A/B, methodology «Style of self–regulation of behavior - SSP-98» by V.I. Morosanova. Results. Low values of the general level of voluntary self-regulation of behavior of adolescents with hepatic encephalopathy are due to a decrease in the severity of regulatory processes of flexibility and independence. The results obtained allow us to conclude that the reduction of planning processes, flexibility and independence, providing a low overall level of arbitrary self-regulation, provide a significant decrease in neurocognitive indicators of prognostic regulation. Conclusions. The revealed qualitative and quantitative features of the regulatory sphere can be considered as one of the predictors in the genesis of hepatic encephalopathy, which make it possible to carry out prognostic diagnosis of the symptoms of the disease in adolescents at the earliest stages of its development, as well as to carry out differential diagnosis of the disease.

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