Features of the Interaction of Cognitive Functions with the Work of the Magnocellular and Parvocellular Systems in Patients with Schizophrenia and Endogenous Depression.

233

Abstract

The article presents a study devoted to the study of cognitive dysfunctions in patients with schizophrenia and endogenous depression in their relationship with the functioning of the magnocellular and parvocellular systems. Mismatch in the work of neural systems leads to violations of the integrity of visual perception and to a violation of the selectivity of thinking in endogenous patients, which makes it difficult to assess and select meaningful, essential information in the formation of judgments. 60 patients with schizophrenia (43 (75%) male and 17 (25%) female; mean age ― 34.0±12.0 years) and 25 patients with endogenous depression (11 (44%) male and 14 (56%) female, mean age ― 38.0±13.6 years) with the use of psychophysiological (the method of visocontrastometry with an assessment of the contrast sensitivity of the visual system, the method of assessing the noise immunity of the visual system) and experimental psychological methods (Trial-Making test by Reitan, Memorizing 10 words, Poppelreiter's figures, Incomplete images, Excluding the 4th superfluous). The established features of cognitive dysfunctions in endogenous depression and schizophrenia are associated with the features of the functional state of the magnocellular and parvocellular neuronal systems and the nature of the interaction of these systems. The specificity of impairments in cognitive functions in patients with endogenous depression is due to changes in the dynamic component of cognitive activity, while the specificity of impairments in cognitive functions in patients with schizophrenia is associated with changes in the selectivity of information and early sensory defects. The data obtained make it possible to develop an idea of the profiles of sensory-cognitive impairments in endogenous depression and schizophrenia, which is of particular importance for differential diagnosis.

General Information

Keywords: visual perception, cognitive processes, magno- and parvocellular systems, contrast sensitivity, thinking, schizophrenia, endogenous depression

Journal rubric: Empirical Research

Article type: scientific article

DOI: https://doi.org/10.17759/cpse.2021100405

Funding. The study was carried out with the financial support of the Russian Foundation for Basic Research (RFBR) within the framework of research project no. 18-013-01245.

Received: 09.01.2021

Accepted:

For citation: Mukhitova Y.V., Isaeva E.R., Tregubenko I.A., Shoshina I.I., Khanko A.V., Limankin O.V. Features of the Interaction of Cognitive Functions with the Work of the Magnocellular and Parvocellular Systems in Patients with Schizophrenia and Endogenous Depression. [Elektronnyi resurs]. Klinicheskaia i spetsial'naia psikhologiia = Clinical Psychology and Special Education, 2021. Vol. 10, no. 4, pp. 93–117. DOI: 10.17759/cpse.2021100405. (In Russ., аbstr. in Engl.)

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Information About the Authors

Yulianna V. Mukhitova, PhD in Psychology, Associate Professor of the Department of Psychology and Clinical Psychology, Pavlov First Saint-Petersburg State Medical University, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0003-4172-6257, e-mail: che88@mail.ru

Elena R. Isaeva, Doctor of Psychology, Professor, Head of the Department of Psychology and Clinical Psychology, The First Pavlov State Medical University of St. Petersburg, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-7731-7693, e-mail: isajeva@yandex.ru

Ilya A. Tregubenko, PhD in Psychology, Associate Professor of the Department of Psychology and Clinical Psychology, Pavlov First Saint-Petersburg State Medical University, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-8836-5084, e-mail: ia2312@yandex.ru

Irina I. Shoshina, Doctor of Biology, Associate Professor, Senior Researcher of the Laboratory of the Vision Physiology, Pavlov Institute of Physiology of the Russian Academy of Science, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-8113-1680, e-mail: shoshinaii@mail.ru

Alexander V. Khanko, PhD in Psychology, Chief of Psychology Service, Psychiatric Hospital No 1 named after P.P. Kashchenko, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0003-1465-2483, e-mail: aleksandrkhanko@yandex.ru

Oleg V. Limankin, Doctor of Medicine, Cheif Doctor, Psychiatric Hospital No 1 named after P.P. Kashchenko, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0001-6318-7536, e-mail: limankin@mail.ru

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