The contribution presents a generalization of modern medical-biological and psychophysiological researches of methods of prevention of psychoemotional stress. The research is relevant because the consequences of emotional stress have a full-scale destructive influence on the life activity of the organism and undermine people’s health. The aim of the contribution is a literary review which analyzes the problem of emotional stress – causes of origin of various neuro-psychical disorders and methods of prevention of originating psychoemotional stress. The main task of the contribution is the analysis of the causes of stress and its possible prevention. It describes the problem areas and questions based on scientific knowledge and existing multiple ways of prevention of undesired consequences of psychoemotional stress and protection of persons exposed to stress.