Features of Physiological Mechanisms of Cognitive Functions in Patients with Schizophrenia Using Different Types of Pharmacotherapy

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Abstract

The article describes results of the study of the neurophysiological mechanisms of cognitive functions associated with the parameters of various cognitive styles. Subjects included schizophreniс patients with paranoid attacks and healthy people. Subjects also made up two groups based on the intake of various types of neuroleptics. Methods: psychological techniques for measuring cognitive styles, SANS. The ERP to different sequences, consisting of standard and deviant stimuli. Results: We have found changes in the neurophysiological mechanisms of cognitive functions depending on cognitive styles and the intake of various types of neuroleptics. Neurophysiological mechanisms of cognitive functions are associated with the short-term memory system and the work of the hippocampal structures that provide the potential of neuronal synapses.

General Information

Keywords: prediction, cognitive styles, EEG, event related potentials, pharmacotherapy, typical antipsychotics, atypical antipsychotics, implicit learning, explicit learning, neuroimaging

Journal rubric: Clinical Psychology and Psychophysiology

Article type: scientific article

For citation: Gorbunov J.A., Chepikova K.A., Gaevsky A.A., Yanichev D.P. Features of Physiological Mechanisms of Cognitive Functions in Patients with Schizophrenia Using Different Types of Pharmacotherapy. Vestnik of Saint Petersburg University. Psychology, 2018. Vol. 8, no. 1, pp. 83–104. (In Russ., аbstr. in Engl.)

References

Anohin P.K. Ocherki po fiziologii funktsional’nykh sistem [ Essays on the Physiology of Functional Systems]. Moscow, Meditsina Publ., 1975. 448 p. (In Russian)

Information About the Authors

Jean A. Gorbunov, PhD in Psychology, Senior Researcher, Clinical Psychology and Psychophysiology Department,, St Petersburg State University, St.Petersburg, Russia, ORCID: https://orcid.org/0000-0002-7558-750X, e-mail: i.a.gorbunov@spbu.ru

Karina A. Chepikova, Postgraduate student, St. Petersburg State University, St.Petersburg, Russia, e-mail: karinach@inbox.ru

Aleksandr A. Gaevsky, St. Petersburg state public institution “Psychiatric Hospital No. 6”, St.Petersburg, Russia, e-mail: gaevskyalexander@gmail.com

Dmitry P. Yanichev, PhD in Psychology, St. Petersburg State University, St.Petersburg, Russia, e-mail: mryanichev@mail.ru

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