Bipolar Affective Disorder. Clinical Aspects and Comorbidity

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Abstract

The review of the literature describes the clinical features of bipolar affective disorder (BAD). Difficulties in diagnosing BAD due to the complex clinical picture that cause untimely diagnosis and the formation of an unfavorable course of the disease are examined in detail. The data on mental disorders it is necessary to differentiate BAD from are presented. The characteristics of the course of BAD are described in detail, including unfavorable forms and mixed bipolar conditions, which are difficult to diagnose and treat, and present a negative prognostic factor. The data on the deterioration of the cognitive abilities of patients with an increase in the number of episodes of BAD, which can occur even during euthymy, are considered. Particular attention is paid to the consideration of forms of mental and somatic pathology, comorbid BAD associated with a decrease in the quality of life, poor prognosis, increased disability, and premature mortality.

General Information

Keywords: bipolar affective disorder (BAR), diagnostic difficulties, clinical picture, comorbidity with mental disorders and somatic diseases

Journal rubric: Research Reviews

Article type: scientific article

DOI: https://doi.org/10.17759/cpp.2020280110

For citation: Dovzhenko T.V., Tsarenko D.M., Yudeeva T.Y. Bipolar Affective Disorder. Clinical Aspects and Comorbidity. Konsul'tativnaya psikhologiya i psikhoterapiya = Counseling Psychology and Psychotherapy, 2020. Vol. 28, no. 1, pp. 166–179. DOI: 10.17759/cpp.2020280110. (In Russ., аbstr. in Engl.)

References

  1. Kuzavkova M.V., Kostyukova E.G., Mosolov S.N. Kliniko-farmakokineticheskii prognoz effektivnosti antikonvul’santov, normotimikov i solei litiya pri vtorichnoi profilaktike shizoaffektivnogo i affektivnogo psikhozov. Novye dostizheniya v terapii psikhicheskikh zabolevanii [Clinical and pharmacokinetic prognosis of the effectiveness of anticonvulsants, normotimics and lithium salts in the secondary prevention of schizoaffective and affective psychoses]. In Mosolov S.N. (ed.). Novye dostizheniya v terapii psikhicheskikh zabolevanii [ New findings in metal disorders therapy]. Moscow: “BINOM. Laboratoriya znanii” Publ., 2002, pp. 356—372.
  2. Mosolov S.N., Kostyukova E.G., Kuzavkova M.V. Bipolyarnoe affektivnoe rasstroistvo: diagnostika i terapiya [Bipolar Affective Disorder: Diagnosis and Therapy]. Moscow: MEDpress-inform, 2008. 384 p.
  3. Allilaire J.F. Diagnosis of Bipolar Disorder and Rationale of Early Treatment. Bulletin de l’Academie nationale de medecine, 2010. Vol. 194 (9), pp. 1695—1703.
  4. Altamura A.C., Dell’Osso B., Berlin H.A., et al. Duration of untreated illness and suicide in bipolar disorder: a naturalistic study. European Archives of Psychiatry and Clinical Neuroscience, 2010. Vol. 260 (5), pp. 385—391.
  5. American Psychiatric Association. Practice guideline for the treatment of patients with bipolar disorder (revision) [Elektronnyi resurs]. 2002 Available at: https:// psychiatryonline.org/pb/assets/raw/sitewide/practice_guidelines/guidelines/ bipolar.pdf (Accessed 10.11.2019). // American Journal of Psychiatry. 2002. Vol. 159. № 4. P. 1—50.
  6. Benazzi F. Prevalence of bipolar II disorder in atypical depression. European Archives of Psychiatry and Clinical Neuroscience, 1999. Vol. 249 (2), pp. 62—65. doi:10.1007/ s004060050067
  7. Benazzi F. Depression with DSM-IV atypical features: a marker for bipolar II disorder. European Archives of Psychiatry and Clinical Neuroscience, 2000. Vol. 250 (1), pp. 53—55. doi:10.1007/s004060050010
  8. Berk M., Hallam K., Lucas N., et al. Early intervention in bipolar disorders: opportunities and pitfalls. Medical Journal of Australia, 2007. Vol. 187 (7), pp. 11— 14. doi:10.5694/j.1326-5377.2007.tb01328.x
  9. Bowden C.L. Strategies to reduce misdiagnosis of bipolar depression. Psychiatric Services, 2001. Vol. 52 (1), pp. 51—55. doi:10.1176/appi.ps.52.1.51
  10. Cassidy F., Carroll B.J. Vascular risk factors in late onset mania. Psychological Medicine, 2002. Vol. 32 (2), pp. 359—362. doi:10.1017/S0033291701004718
  11. Crump C., Sundquist K., Winkleby M.A., et al. Comorbidities and- mortality in bipolar disorder: Swedish national cohort study. JAMA Psychiatry, 2013. Vol. 70 (9), pp. 931—939. doi:10.1001/jamapsychiatry.2013.1394
  12. George E.L., Miklowitz D.J., Richards J.A., et al. The comorbidity of bipolar disorder and axis II personality disorders: prevalence and clinical correlates. Bipolar Disorders, 2003. Vol. 5 (2), pp. 115—122. doi:10.1034/j.1399- 5618.2003.00028.x
  13. Goldberg J.F., Harrow M. Consistency of remission and outcome in bipolar and unipolar mood disorders: a 10-year prospective follow-up. Journal of Affective Disorders, 2004. Vol. 81 (2), pp. 123—131. doi:10.1016/S0165-0327(03)00161-7
  14. González-Pinto A., Barbeito S., Alonso M., et al. Poor long-term prognosis in mixed bipolar patients: 10-year outcomes in the Vitoria prospective naturalistic study in Spain. The Journal of Clinical Psychiatry, 2011. Vol. 72 (5), pp. 671—676. doi:10.4088/JCP.09m05483yel
  15. Goodwin F.K., Jamison K.R. Manic-Depressive Illness: Bipolar Disorders and Recurrent Depression. 2nd ed. New York; Oxford: University Press, 2007. 1262 p.
  16. Hayes J.F., Miles J., Walters K., et al. A systematic review and meta-analysis of premature mortality in bipolar affective disorder. Acta Psychiatrica Scandinavica, 2015. Vol. 131 (6), pp. 417—425. doi:10.1111/acps.12408
  17. Hirschfeld R.M.A., Lewis L., Vornik L.A. Perceptions and impact of bipolar disorder: How far have we really come? Results of the National Depressive and Manic- Depressive Association 2000 survey of individuals with bipolar disorder. The Journal of Clinical Psychiatry, 2003. Vol. 64 (2), pp. 161—174. doi:10.4088/JCP.v64n0209
  18. Joyce K., Thompson A., Marwaha S. Is treatment for bipolar disorder more effective earlier in illness course? A comprehensive literature review [Elektronnyi resurs]. International Journal of Bipolar Disorders, 2016. Vol. 4 (1). Available at: journalbipolardisorders.springeropen.com/articles/10.1186/s40345-016-0060-6 (Accessed 18.11.2019). doi:10.1186/s40345-016-0060-6
  19. Keck P.E.J., McElroy S.L., Strakowski S.M., et al. Twelve-month outcome of patients with bipolar disorder following hospitalization for a manic or mixed episode. American Journal of Psychiatry, 1998. Vol. 67 (11), pp. 28—33.
  20. Kennedy S.H., Lam R.W., Parikh S.V., et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. Introduction . Journal of Affective Disorders, 2009. Vol. 117 (S1), pp. S1—S2. doi:10.1016/j.jad.2009.06.043.
  21. Kessler R.C., McGonagle K.A., Zhao S., et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Archives of General Psychiatry, 1994. Vol. 51 (1), pp. 8—19.
  22. Kilbourne A., Cornelius J., Han X., et al. Burden of general medical conditions among individuals with bipolar disorder. Bipolar Disorders, 2004. Vol. 6 (5), pp. 368—373. doi:10.1111/j.1399-5618.2004.00138.x
  23. Krahn G.L. WHO World Report on Disability: A review. Disability and Health Journal, 2011. Vol. 4 (3), pp. 141—142. doi:10.1016/j.dhjo.2011.05.001
  24. Kroon J.S., Wohlfarth T.D., Dieleman J., et al. Incidence rates and risk factors of bipolar disorder in the general population: a population-based cohort study. Bipolar Disorders, 2013. Vol. 15 (3), pp. 306—313. doi:10.1111/bdi.12058
  25. Kupfer D.J. Increasing medical burden in bipolar disorder. JAMA, 2005. Vol. 293 (20), pp. 2528—2530. doi:10.1001/jama.293.20.2528
  26. Magalhães P.V., Kapczinski F., Nierenberg A.A., et al. Illness burden and medical comorbidity in the Systematic Treatment Enhancement Program for Bipolar Disorder. Acta Psychiatrica Scandinavica, 2012. Vol. 125 (4), pp. 303—308. doi:10.1111/j.1600-0447.2011.01794.x
  27. Mansfield A.K, Dealy J.A., Keitner G.I. Family interventions for bipolar disorder: a review of the literature. Neuropsychiatry, 2012. Vol. 2 (3), pp. 231—238. doi:10.2217/ npy.12.27
  28. Mantere O., Isometsä E., Ketokivi M., et al. A prospective latent analyses study of psychiatric comorbidity of DSM-IV bipolar I and II disorders. Bipolar Disorders, 2010. Vol. 12 (3), pp. 271—284. doi:10.1111/j.1399-5618.2010.00810.x
  29. McElroy S.L. Understanding the complexity of bipolar mixed episodes. The Journal of Clinical Psychiatry, 2008. Vol. 69 (2), p. e06. doi:10.4088/JCP.0208e06
  30. Merikangas K.R., Jin R., He J.P., et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Archives of General Psychiatry, 2011. Vol. 68 (3), pp. 241—251. doi:10.1001/archgenpsychiatry.2011.12
  31. Motovsky B., Pecenak J. Psychopathological characteristics of bipolar and unipolar depression — potential indicators of bipolarity. Psychiatria Danubina, 2013. Vol. 25 (1), pp. 34—39.
  32. Ng T.H., Burke,T.A., Stange J.P., et al. Personality disorder symptom severity predicts onset of mood episodes and conversion to bipolar I disorder in individuals with bipolar spectrum disorder. Journal of Abnormal Psychology, 2017. Vol. 126 (3), pp. 271—284. doi:10.1037/abn0000255
  33. Øiesvold T., Nivison M., Hansen V., et al. Classification of bipolar disorder in psychiatric hospital. A prospective cohort study [Elektronnyi resurs]. BMC Psychiatry, 2012. Vol. 12. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC3317873/ (Accessed 21.11.2019). doi:10.1186/1471-244X-12-13
  34. Perugi G., Akiskal H.S., Micheli C., et al. Clinical subtypes of bipolar mixed states: validating a broader European definition in 143 cases. Journal of Affective Disorders, 1997. Vol. 43 (3), pp. 169—180.
  35. Post R.M., Leverich G.S., Kupka R.W., et al. Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. The Journal of Clinical Psychiatry, 2010. Vol. 71 (7), pp. 864—872. doi:10.4088/JCP.08m04994yel
  36. Price A.L., Marzani-Nissen G.R. Bipolar disorders: A review. American Family Physician, 2012. Vol. 85 (5), pp. 483—493.
  37. Suppes T., Leverich G.S., Keck P.E., et al. The Stanley Foundation Bipolar treatment outcome Network II. Demographics and illness characteristics of the first 261 patients. Journal of Affective Disorders, 2001. Vol. 67, pp. 45—59. doi:10.1016/ S0165-0327(01)00432-3
  38. Suppes T., Kelly D.I., Perla J.M. Challenges in the management of bipolar depression. The Journal of Clinical Psychiatry, 2005. Vol. 66 (5), pp. 11—16.
  39. Swann A.C., Lafer B., Perugi G., et al. Bipolar mixed states: an international society for bipolar disorders task force report of symptom structure, course of illness, and diagnosis. American Journal of Psychiatry, 2013. Vol. 170 (1), pp. 31—42. doi:10.1176/appi.ajp.2012.12030301
  40. Valenti E.A., Pacchiarotti I., Rosa A.R., et al. Bipolar mixed episodes and antidepressants: a cohort study of bipolar I disorder patients. Bipolar Disorders, 2011. Vol. 13 (2), pp. 145—154. doi:10.1111/j.1399-5618.2011.00908.x
  41. Vázquez G.H., Baldessarini R.J., Tondo L. Co-occurrence of anxiety and bipolar disorders: clinical and therapeutic overview. Depression and Anxiety, 2014. Vol. 31 (3), pp. 196—206. doi:10.1002/da.22248
  42. Vieta E., Rosa A.R. Evolving trends in the long-term treatment of bipolar disorder. The World Journal of Biological Psychiatry, 2007. Vol. 8 (1), pp. 4—11. doi:10.1080/15622970601083280
  43. Vieta E. Managing Bipolar Disorder in Clinical Practice. 2nd ed. 3rd ed. 2009 London: Springer Healthcare, 2013. 127 149 p.

Information About the Authors

Tatyana V. Dovzhenko, Doctor of Medicine, Professor, Chief Researcher, Laboratory of Psychological Counseling and Psychotherapy, Moscow Research Institute of Psychiatry - Federal Budgetary Institution "V. Serbsky National Medical Research Centre for Psychiatry and Narcology" of the Ministry of Health of Russia, Moscow, Russia, e-mail: dtv99@mail.ru

Dmitry M. Tsarenko, PhD in Medicine, senior researcher, Laboratory of Psychological Counseling and Psychotherapy, Moscow Research Institute of Psychiatry— Branch of The Serbsky Federal Medical Research Center for Psychiatry and Narcology, Moscow, Russia, e-mail: dropship@rambler.ru

Tatianaatiana Y. Yudeeva, PhD in Psychology, Associate Professor, Senior Researcher, Laboratory of Psychological Counseling and Psychotherapy, Moscow Research Institute of Psychiatry — Branch of The Serbsky Federal Medical Research Center for Psychiatry and Narcology, Moscow, Russia, e-mail: tatiana.yudeeva@yandex.ru

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