Conformity to natural laws of memory remodeling of skills, formed at the single- and multi-stage training

In this research we tested if the neuronal bases of one-stage or several-stage acquired skills are identical. In order to do this we analyzed the link between the neurogenetic changes during additional learning and the number of stages during previous learning. To answer this question we trained two groups of animals in one stage or several stages, re-trained them the same skill on the other side of the experimental chamber and evaluated the number of neurons with change gene expression. While the animals of both groups demonstrated similar behavior during additional learning, the number of neurons with changed gene expression differed significantly. Thus we demonstrated that accommodative reconsolidation processes (reorganization of previously acquired individual experience) are dependent on previous learning history.

1. Alexandrov Yu. I., Grechenko T. N., Gavrilov V. V. i dr. Zakonomernosti formirovaniya i realizacii individual'nogo opyta // Zhurn. vyssh. nerv. deyat. 1997. T. 47. № 2. S. 243–260.
2. Anohin K. V. Molekulyarnye scenarii konsolidacii dolgovremennoy pamyati // Zhurn. vyssh. nerv. deyat. 1997. T. 47. № 2. S. 261–279.
3. Svarnik O. E. Mehanizmy reorganizacii individual'nogo opyta pri nauchenii // Materialy itogovoy nauchnoy konferencii Instituta psihologii RAN. M.: Izd. «Institut psihologii RAN», 2010. S. 250–259.
4. Svarnik O. E., Alexandrov Yu. I., Anohin K. V. Generaciya novyh gipotez pri obuchenii i indukciya iekspressii gena c-fos v neyronah golovnogo mozga // XX s'ezd Fiziologicheskogo obschestva im. I. P. Pavlova. Tezisy dokladov. M.: Izdatel'skiy dom «Russkiy vrach», 2007. S. 85.
5. Shvyrkov V. B. Vvedenie v ob'ektivnuyu psihologiyu. Neironal'nye osnovy psihiki / Pod red. Yu. I. Alexandrova. M.: Izd. IP RAN, 1995.