Психофизиологические и молекулярно-генетические корреляты утомления

Настоящая статья посвящена теоретическому обзору в области изучения утомления, и, в частности, современным данным о психофизиологических и молекулярно-генетических коррелятах утомления. В настоящее время существует множество методов, используемых для оценки утомления и других функциональных состояний: субъективные, поведенческие и психофизиологические методы. Прежде исследования в области утомления в основном были направлены на поиск какого-либо объективного индикатора данного состояния. В современных же исследованиях акцент делается на комплексном подходе. В последние годы огромное развитие получила молекулярная биология, что отразилось на качественном улучшении и росте числа исследований и публикаций, демонстрирующих связь между наличием определенных полиморфизмов генов и проявлением поведенческих паттернов или физиологических реакций. Таким образом, в настоящей работе сделана попытка отразить существующие психофизиологические и молекулярно-генетические корреляты утомления.

1. Влияние функционального полиморфизма Val158Met катехол-О-метилтрансферазы на физическую агрессивность / М.А. Куликова [и др.] // Бюллетень экспериментальной биологии и медицины. 2008. Т. 145. № 1. С. 68–71.
2. От нейрона к мозгу / Дж. Г. Николлс [и др.] // М.: Издательство ЛКИ, 2008. 672 с.
3. Поликанова И.С., Сергеев А.В. Влияние длительной когнитивной нагрузки на параметры ЭЭГ [Электронный ресурс] // Национальный психологический журнал. 2014. № 1(13). С. 84–92. URL: http://cyberleninka.ru/article/n/vliyanie-dlitelnoy-kognitivnoy-nagruzki-na-parametry-eeg (дата обращения: 10.01.2017).
4. Психология спорта / Ю.П. Зинченко [и др.]. М.: Изд-во Моск. ун-та, 2011. 424 c.
5. Эрисман Ф.Ф. Профессиональная гигиена или гигиена умственного и физического труда. Спб.: Тип. М.М. Стасюлевича, 1877. 406 с.
6. A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus / K.K. Kidd [et al.] // Human Genetics. 1998. Vol. 103. № 2. P. 211–227. doi: 10.1007/s004390050809
7. A novel method for the determination of the EEG individual alpha frequency / A. Goljahani [et al.] // Neuroimage. 2012. Vol. 60. № 1. P. 774–786. doi: 10.1016/j.neuroimage.2011.12.001
8. Adayev T., Ranasinghe B., Banerjee P. Transmembrane signaling in the brain by serotonin, a key regulator of physiology and emotion // Bioscience Reports. 2005. Vol. 25. № 5–6. P. 363–385. doi: 10.1007/s10540-005-2896-3
9. Aggression and 5HTT polymorphism in females: Study of synchronized swimming and control groups / O.V. Sysoeva [et al.] // International Journal of Psychophysiology. 2009. Vol. 72. № 2. P. 173–178. doi: 10.1016/j.ijpsycho.2008.12.005
10. Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype / G. Jones [et al.] // The British Journal of Psychiatry. 2001. Vol. 179. № 4. P. 351–355. doi: 10.1192/bjp.179.4.351
11. Analysis of a functional catechol O-methyltransferase gene polymorphism in schizophrenia: evidence for association with aggressive and antisocial behavior / R.D. Strous [et al.] // Psychiatry Research. 1997. Vol. 69. № 2–3. P. 71–77. doi: 10.1016/S0165-1781(96)03111-3
12. Association between catechol O-methyltransferase genotype and violence in schizophrenia and schizoaffective disorder [Электронный ресурс] / H.M. Lachman [et al.] // American Journal of Psychiatry. 1998. Vol. 155. № 6. P. 835–837. URL: http://ajp.psychiatryonline.org/doi/pdf/10.1176/ajp.155.6.835 (дата обращения: 11.01.2017).
13. Association between polymorphisms of the dopamine receptor D2 and catechol-o-methyl transferase genes and cognitive function / J.L. Bolton [et al.] // Behavior Genetics. 2010. Vol. 40. № 5. P. 630–638. doi: 10.1007/s10519-010-9372-y
14. Association between serotonin transporter gene polymorphism and chronic fatigue syndrome / M. Narita [et al.] // Biochemical and Biophysical Research Communications. 2003. Vol. 19. № 11. P. 1348–1351. doi: 10.1002/mds.20191
15. Association of polymorphisms of dopamine D2 receptor (DRD2), and dopamine transporter (DAT1) genes with schizoid/avoidant behaviors (SAB) / K. Blum [et al.] // Molecular Psychiatry. 1997. Vol. 2. № 1. P. 239–246. doi: 10.1016/S0006-3223(97)88120-6
16. Balaban C.D. Neural substrates linking balance control and anxiety // Physiology&Behavior. 2002. Vol. 77. № 4–5. P. 469–475. doi: 10.1016/S0031-9384(02)00935-6
17. Blomstrand E. Amino acids and central fatigue // Amino Acids. 2001. Vol. 20. № 1. P. 25–34. doi: 10.1007/s007260170063
18. Boksem M.A.S., Meijman T.F., Lorist M.M. Mental fatigue, motivation and action monitoring // Biological Psychology. 2006. Vol. 72. № 2. P. 123–132. doi: 10.1016/j.biopsycho.2005.08.007
19. Catechol O-methyl transferase and dopamine D2 receptor gene polymorphisms: evidence of positive heterosis and gene-gene interaction on working memory functioning / M.F. Gosso [et al.] // The American Journal of Human Genetics. 2008. Vol. 16. P. 1075–1082. doi: 10.1038/ejhg.2008.57
20. Cheng S.Y., Hsu H.T. Mental Fatigue Measurement Using EEG // Risk Management Trends / Ed. By Giancarlo Nota. 2011. P. 266[Р1] .
21. Clinical neurophysiology: Electroencephalography, Paediatric Neurophysiology, Special Techniques and Applications. Vol. 2. / C.D. Binnie [et al.]. Amsterdam; London: Elsevier, 2003. 993 p.
22. Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR / J.H. Barnett [et al.] // American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 2011. Vol. 156. № 2. P. 158–167. doi: 10.1002/ajmg.b.31150
23. D2 dopamine receptor gene (DRD2) TaqI A polymorphism: Reduced D2 receptor binding in the human striatum associated with the A1 allele / J. Thompson [et al.] // Pharmacogenetics. 1997. Vol. 7. № 6. P. 479–484.
24. Davis J.M. Carbohydrates, branched-chain amino acids, and endurance: the central fatigue hypothesis // International journal of sport nutrition. 1995. Vol. 5. № s1. P. [Р2] S29–S38.
25. Davis J.M., Alderson N.L., Welsh R.S. Serotonin and central nervous system fatigue: nutritional considerations // The American Journal of Clinical Nutrition. 2000. Vol. 72. № 2. P. 573–578.
26. Davis J.M., Bailey S.P. Possible mechanisms of central nervous system fatigue during exercise // Medicine and Science in Sport and Exercise. 1997. Vol. 29. № 1. P. 45–57. doi: 10.1097/00005768-199701000-00008
27. Dopamine D2 receptor and N-methyl-D-aspartate receptor 2B subunit genetic variants and intelligence / S.J. Tsai [et al.] // Neuropsychobiology. 2002. Vol. 45. № 3. P. 128–130. doi: 10.1159/000054951
28. EEG-based Estimation of Cognitive Fatigue [Электронный ресурс] / L.J. Trejo [et al.] // Proceedings of Symposium OR05 Defense and Security. 2005. Vol. 5797. P. 105–115. URL: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.330.2239&rep=rep1&type=pdf (дата обращения: 10.01.2017).
29. EEG-Based Estimation of Mental Fatigue: Convergent Evidence for a Three-State Model / L.J. Trejo [et al.] // Foundations of Augmented Cognition / Eds. D.D. Schmorrow, L.M. Reeves. Berlin: Springer, 2007. P. 201–211. (Lecture Notes in Computer Science; Vol. 4565). doi: 10.1007/978-3-540-73216-7_23
30. Epstein H.T. EEG developmental stages // Developmental Psychobiology. 1980. Vol. 13. № 6. P. 629–631. doi: 10.1002/dev.420130608
31. Fatigue as a Window to the Brain / Ed. By DeLuca E. Cambridge, London: The MIT Press, 2005. 357 p.
32. Fernstrom J.D., Fernstrom M.H. Exercise, serum free tryptophan, and central fatigue // Journal of Nutrition. 2006. Vol. 136. № 2. P. 553–559.
33. Foley T.E., Fleshner M. Neuroplasticity of dopamine circuits after exercise: implications for central fatigue // NeuroMolecular Medicine. 2008. Vol. 10. № 2. P. 67–80. doi: 10.1007/s12017-008-8032-3
34. Human striatal dopamine receptors are organized in compartments [Электронный ресурс] / N.J. Joyce [et al.] // Proceedings of the National Academy of Sciences. 1986. Vol. 83. № 20. P. 8002–8006. URL: https://www.researchgate.net/profile/Jeffrey_Joyce/publication/20211466_Human_striatal_dopamine_receptors_are_organized_in_patches/links/00b495169e8fe12569000000.pdf (дата обращения: 11.01.2017).
35. Identification of first candidate genes for creativity: A pilot study / M. Reuter [et al.] // Brain Research. 2006. Vol. 1069. № 1. P. 190–197. doi: 10.1016/j.brainres.2005.11.046
36. Insular dopamine D2 receptors and novelty seeking personality in Parkinson's disease / V. Kaasinen [et al.] // Movement Disorders. 2004. Vol. 19. № 11. P. 1348–1351. doi: 10.1002/mds.20191
37. Klimesch W. EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis // Brain Research Reviews. 1999. Vol. 29. № 2–3. Р. 169–195. doi: 10.1016/S0165-0173(98)00056-3
38. Klimesch W. EEG-alpha rhythms and memory processes // International Journal of Psychophysiology. 1997. Vol. 26. № 1–3. P. 319–340. doi: 10.1016/S0167-8760(97)00773-3
39. Knight J.L., Kantowitz B.H. Speed-accuracy tradeoff in double stimulation: Effects on the first response // Memory & Cognition. 1974. Vol. 2. № 3. P. 522–532. doi: 10.3758/BF03196915
40. Lal S., Bekiaris E. The Reliability of Sensing Fatigue from Neurophysiology [Электронный ресурс] // Auswireless Conference, University of Technology, Sydney. 2007. URL: https://opus.lib.uts.edu.au/handle/2100/87 (дата обращения: 10.01.2017).
41. Lesch K.P., Merschdorf U. Impulsivity, aggression, and serotonin: a molecular psychobiological perspective // Behavioral Sciences & the Law. 2000. Vol. 18. № 5. P. 581–604. doi: 10.1002/1099-0798(200010)18:5<581::AID-BSL411>3.0.CO;2-L
42. Lorist M.M., Boksem M.A.S., Ridderinkhof K.R. Impaired cognitive control and reduced cingulate activity during mental fatigue // Cognitive Brain Research. 2005. Vol. 24. № 2. P. 199–205. doi: 10.1016/j.cogbrainres.2005.01.018
43. Meeusen R., Watson P. Amino acids and the brain: do they play a role in «central fatigue»? // International journal of sport nutrition and exercise. 2007. Vol. 17. P. 37–46. doi: 10.1123/ijsnem.17.s1.s37
44. Mental fatigue and task control: Planning and preparation / M.M. Lorist [et al.] // Psychophysiology. 2000. Vol. 37. № 5. P. 614–625. doi: 10.1111/1469-8986.3750614
45. Murataa A., Uetakeb A., Takasawab Y. Evaluation of mental fatigue using feature parameter extracted from event-related potential // Journal of Industrial Ergonomics. 2005. Vol. 35. № 8. P. 761–770. doi: 10.1016/j.ergon.2004.12.003
46. Newsholme E.A., Blomstrand E. Tryptophan 5-hydroxytryptamine and a possible explanation for central fatigue // Advances in Experimental Medicine and Biology. 1995. Vol. 384. P. 315–320.
47. Newsholme E.A., Blomstrand E., Ekblom B. Physical and mental fatigue: metabolic mechanisms and importance of plasma amino acids // British Medical Bulletin. 1992. Vol. 48. № 3. P. 477–95. doi: 10.1093/oxfordjournals.bmb.a072558
48. Nieoullon A. Dopamine and the regulation of cognition and attention // Progress in Neurobiology. 2002. Vol. 67. № 1. P. 53–83. doi: 10.1016/S0301-0082(02)00011-4
49. Nucleus accumbens dopamine and rate of responding: Neurochemical and behavioral studies / J.D. Salamone [et al.] // Psychobiology. 1999. Vol. 27. № 2. P. 236–247. doi: 10.3758/BF03332117
50. Ollman R. Fast guess in choice reaction time // Psychonomic Science. 1966. Vol. 6. № 4. P. 155–156. doi: 10.3758/BF03328004
51. Palmatier M.A., Kang A.M., Kidd K.K. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles // Biological Psychiatry. 1999. Vol. 46. № 4. P. 557–567. doi: 10.1016/S0006-3223(99)00098-0
52. Peak alpha frequency: an electroencephalographic measure of cognitive preparedness / E. Angelakis [et al.] // Clinical Neurophysiology. 2004. Vol. 115. № 4. P. 887–897. doi: 10.1016/j.clinph.2003.11.034
53. Petersen I., Eeg-Olofsson O. The development of the electroencephalogram in normal children from the age of 1 through 15 years – Non-paroxysmal activity // Neuropаdiatrie. 1971. Vol. 2. № 3. P. 375–404.
54. Polikanova I.S., Sysoeva O.V., Tonevitsky A.G. Association between serotonin transporter (5HTT) and mental fatigue development [Электронный ресурс] // Psikhologicheskie Issledovaniya. 2012. Vol. 5. № 24. URL: http://psystudy.ru/index.php/eng/2012v5n24e/717-polikanova24e.html (дата обращения: 12.01.2017).
55. Polikanova I.S., Sysoeva O.V., Tonevitsky A.G. Association between 5HTT polymorphism and cognitive fatigue development // International Journal of Psychophysiology (Special Issue). 2012. Vol. 3. № 85. P. 411–411. doi: 10.1016/j.ijpsycho.2012.07.128
56. Ritchie T., Noble E.P. Association of seven polymorphisms of the D2 dopamine receptor gene with brain receptor-binding characteristics // Neurochemical Research. 2003. Vol. 28. № 1. P. 73–82. doi: 10.1023/A:1021648128758
57. Salamone J.D. Involvement of nucleus accumbens dopamine in behavioral activation and effort-related functions: Dopamine handbook. Oxford; New York: Oxford University Press, 2010. 286 p.
58. Salamone J.D. Motor function and motivation // Encyclopedia of behavioral neuroscience / Eds. G.F Koob, M.L. Moal, R.F. Thompson. London : Academic Press, 2010. P. 267–276.
59. Shifting of activation center in the brain during muscle fatigue: an explanation of minimal central fatigue? / J. Z. Liu [et al.] // Neuroimage. 2007. Vol. 35. № 1. P. 299–307. doi: 10.1016/j.neuroimage.2006.09.050
60. Stein D.J., Stahl S. Serotonin and anxiety: current models // International Clinical Psychopharmacology. 2000. Vol. 15. P. 1–6.
61. Tamminga C.A., Nemeroff C.B., Blakely R.D. Developing novel treatments for mood disorders: accelerating discovery // Biological Psychiatry. 2002. Vol. 52. № 6. P. 589–609. doi: 10.1016/S0006-3223(02)01470-1
62. Test–retest reliability of EEG spectral parameters during cognitive tasks: I. Absolute and relative power / T. Fernandez [et al.] // International Journal of Neuroscience. 1993. Vol. 68. № 3–4. P. 255–261. doi: 10.3109/00207459308994281
63. The influence of mental fatigue and motivation on neural network dynamics; an EEG coherence study / M.M. Lorista [et al.] // Brain Research. 2009. Vol. 1270. P. 95–106. doi: 10.1016/j.brainres.2009.03.015
64. The Molecular Genetics of Executive Function: Role of Monoamine System Genes / J.M. Barnes [et al.] // Biological Psychiatry. 2011. Vol. 69. № 12. P. 127–143. doi: 10.1016/j.biopsych.2010.12.040
65. Using EEG spectral components to assess algorithms for detecting fatigue / B.T. Jap [et al.] // Expert Systems with Applications. 2009. Vol. 36. № 2. P. 2352–2359. doi: 10.1016/j.eswa.2007.12.043
66. Weicker H., Strüder H.K. Influence of exercise on serotonergic neuromodulation in the brain // Amino Acids. 2001. Vol. 20. № 1. P. 35–47. doi: 10.1007/s007260170064
67. Wickelgren W.A. Speed-accuracy tradeoff and information processing dynamics // Acta Psychologica. 1977. Vol. 41. № 1. P. 67–85. doi: 10.1016/0001-6918(77)90012-9
68. Wijesuriya N., Tran Y., Craig A. The psychophysiological determinants of fatigue // International Journal of Psychophysiology. 2007. Vol. 63. № 1. P. 77–86. doi: 10.1016/j.ijpsycho.2006.08.005
69. Wood C.C., Jennings J.R. Speed-accuracy tradeoff functions in choice reaction time: Experimental designs and computational procedures // Perception & Psychophysics. 1976. Vol. 19. № 1. P. 92–102. doi: 10.3758/BF03199392
70. Yellott Jr., John I. Correction for fast guessing and the speed-accuracy tradeoff in choice reaction time // Journal of Mathematical Psychology. 1971. Vol. 8. № 2. P. 159–199. doi: 10.1016/0022-2496(71)90011-3

PlumX

Метрики публикации